Department of Neurobiology
Strick, Peter L.
Distinguished Professor & Chair of Neurobiology, University of Pittsburgh, School of Medicine (primary appoint.)
Thomas Detre Endowed Chair in Neuroscience
Professor, Depts. of Neurological Surgery, Physical Medicine & Rehabilitation, and Psychiatry (second. appoints.)
Co-Director of the Center for Neuroscience at the University of Pittsburgh (CNUP)
Director, Systems Neuroscience Institute (SNI)
Director, Neuroscience Imaging Center (NIC)
Scientific Director, University of Pittsburgh Brain Institute (UPBI)

Campus Address: 4074 BST3
Mailing Address:
  3501 Fifth Ave, STE 4074
  Pittsburgh, PA 15213-3301
Tel: 412-383-9961
Fax: 412-383-9061
Website: (lab access only)

Dr. Strick's research focuses on 4 major topics: (i) the motor areas of the cerebral cortex- their involvement in movement generation and control, as well as in motor skill acquisition and retention; (ii) the motor, cognitive and affective functions of the basal ganglia and cerebellum; (iii) the neural basis for the mind-body connection; and (iv) unraveling the complex neural networks that comprise the central nervous system.

Select Publications:

Cortical motor areas:

The motor cortex communicates with the kidney.
Levinthal DJ, Strick PL.
J Neurosci. 2012 May 9;32(19):6726-31.

Subdivisions of primary motor cortex based on cortico-motoneuronal cells.
Rathelot JA, Strick PL.
Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):918-23.

Muscle representation in the macaque motor cortex: an anatomical perspective.
Rathelot JA, Strick PL.
Proc Natl Acad Sci U S A. 2006 May 23;103(21):8257-62.

The origin of corticospinal projections from the premotor areas in the frontal lobe.
Dum RP, Strick PL.
J Neurosci. 1991 Mar;11(3):667-89.

Muscle and movement representation in M1:

Corticomotoneuronal cells are "functionally tuned".
Griffin DM, Hoffman DS, Strick PL.
Science. 2015 Nov 6;350(6261):667-70.

Direction of action is represented in the ventral premotor cortex.
Kakei S, Hoffman DS, Strick PL.
Nat Neurosci. 2001 Oct;4(10):1020-5.

Muscle and movement representations in the primary motor cortex.
Kakei S, Hoffman DS, Strick PL.
Science. 1999 Sep 24;285(5436):2136-9.

Motor skill acquisition and retention:

Extended practice of a motor skill is associated with reduced metabolic activity in M1.
Picard N, Matsuzaka Y, Strick PL.
Nat Neurosci. 2013 Sep;16(9):1340-7.

Skill representation in the primary motor cortex after long-term practice.
Matsuzaka Y, Picard N, Strick PL.
J Neurophysiol. 2007 Feb;97(2):1819-32.

Activation of the supplementary motor area (SMA) during performance of visually guided movements.
Picard N, Strick PL.
Cereb Cortex. 2003 Sep;13(9):977-86.

Motor areas of the medial wall: a review of their location and functional activation.
Picard N, Strick PL.
Cereb Cortex. 1996 May-Jun;6(3):342-53. Review.

Basal ganglia and cerebellar connections with the cerebral cortex and with each other:

The basal ganglia communicate with the cerebellum.
Bostan AC, Dum RP, Strick PL.
Proc Natl Acad Sci U S A. 2010 May 4;107(18):8452-6.

The cerebellum communicates with the basal ganglia.
Hoshi E, Tremblay L, Féger J, Carras PL, Strick PL.
Nat Neurosci. 2005 Nov;8(11):1491-3.

Cerebellar loops with motor cortex and prefrontal cortex of a nonhuman primate.
Kelly RM, Strick PL.
J Neurosci. 2003 Sep 10;23(23):8432-44.

Parallel organization of functionally segregated circuits linking basal ganglia and cortex.
Alexander GE, DeLong MR, Strick PL.
Annu Rev Neurosci. 1986;9:357-81. Review.

Development of transneuronal tracing with neurotropic viruses:

Transneuronal tracing with neurotropic viruses reveals network macroarchitecture.
Dum RP, Strick PL.
Curr Opin Neurobiol. 2013 Apr;23(2):245-9.

Rabies as a transneuronal tracer of circuits in the central nervous system.
Kelly RM, Strick PL.
J Neurosci Methods. 2000 Nov 15;103(1):63-71. Review.

Direction of transneuronal transport of herpes simplex virus 1 in the primate motor system is strain-dependent.
Zemanick MC, Strick PL, Dix RD.
Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):8048-51.


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