This group investigates receptors that mediate excitatory and inhibitory synaptic responses, synaptic efficacy and function, and neurotransmitter transporter biology, with the aim of uncovering the molecular basis of psychiatric and neurological disease.

Problems of cellular homeostasis and communication are assessed using state-of-the-art molecular biological and biochemical techniques, including:

• fluorescence imaging
• patch-clamp electrophysiology
• computational methods employed to study protein structure and subunit assembly.

This group is complemented by faculty in the Departments of Pharmacology, Computational Biology, Pathology, Psychiatry, and Neurology who investigate related issues of cell signaling and protein interactions in diseases of the nervous system.

Consult the list of affiliated faculty for further information on our research in Cellular Neurobiology.

* Image from Donnelly Lab